… of apicoplast FAS II … apicoplast FAS II functions and parasite survival and pathogenesis.
Our genetic model also offers a platform to dissect the integration of the apicoplast into parasite …

… De novo fatty acid synthesis was monitored in wild type parasites and in … Apicoplast fatty
acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii. …

… Toxoplasma gondii is a common protozoan parasite that infects a … for the parasite's survival.
Here we examined the … Among the aforementioned pathways of fatty acid biogenesis, FAS2 …

… Although the FASII fatty acid biosynthesis pathway located in the apicoplast is essential for
parasite survival, the cellular … loss and defects in its morphology and biogenesis along the T. …

… An apicoplast-located fatty acid synthesis is dispensable in … mitochondrion and the apicoplast
of Toxoplasma gondii. The … organelles of Apicomplexa are crucial for parasite survival in …

… that FASII inhibition results in pronounced apicoplast biogenesis defects in T. … an apicoplast
FASII for de novo synthesis of fatty acids, and this synthesis is essential to parasite survival. …

… Whereas the apicoplast's function has been discussed since its discovery [13], it became
rapidly obvious that this organelle was essential for parasite survival, at least in Plasmodium …

… and Toxoplasma gondii both belong to this phylum and are … /organelle biogenesis, and
parasite survival and propagation. … is a major apicoplast product essential for the parasite survival …

… fatty acid synthesis pathway (FASII). These fatty acids are either exported out of the apicoplast
… cyst-forming apicomplexan parasites such as Toxoplasma gondii and Neospora caninum. …

… essential combination of fatty acids (FAs), obtained from de novo synthesis and host … in
the cytosol of the parasites enter the apicoplast via the apicoplast phosphate transporter (APT). …